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Sorbitol

Sorbitol

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Sorbitol, also known as glucitol, is a sugar alcohol that the body metabolises slowly. It is obtained by reduction of glucose changing the aldehyde group to an additional hydroxyl group hence the name sugar alcohol.

Sweetener
Sorbitol is used in "sugar-free" mints and various cough syrups and is usually listed under the inactive ingredients.

Sorbitol is a sugar substitute often used in diet foods (including diet drinks and ice cream) and sugar-free chewing gum. It also occurs naturally in many stone fruits and berries from trees of the genus Sorbus[1]. Sorbitol is also referred to as a nutritive sweetener because it provides dietary energy: 2.6 kilocalories (11 kilojoules) per gram versus the average 4 kilocalories (17 kilojoules).


Laxative
Sorbitol can be used as a non-stimulant laxative as either an oral suspension or suppository. The drug works by drawing water into the large intestine, thereby stimulating bowel movements. [2] Sorbitol has been determined safe to use in the elderly although it is by no means recommended.


Medical importance
Sorbitol is used in bacterial culture media to distinguish Escherichia_coli_O157_H7 from most other strains of E Coli.

In some human enzymes deficiencies, sorbitol excess arises and can cause damage to the body, although in individuals without certain genetic mutations, it is normal part in the chain of carbohydrate metabolism. An example of such a disease is galactosaemia. In diabetes mellitus, the enzyme is not present in sufficient quantities in some tissue, such as the lens of the eye. Consequently, sorbitol can build up causing cataracts.

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